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ALC Acetyl-L-Carnitine
The amino acid acetyl-L-carnitine (ALC) is required for energy metabolism and synthesis of fatty acids. L-carnitine may significantly reduce the severity of ADHD symptoms; however, inconsistent findings and design flaws limit the significance of these findings. In a multisite 16-week pilot study, 112 children with ADHD were randomized to placebo versus ALC (500 to 1500 mg bid). Children in the ALC group with predominantly inattentive-type ADHD experienced greater improvement over placebo, but there was no differential benefit in children with combined-type ADHD.15
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